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KMID : 1161420110140111448
Journal of Medicinal Food
2011 Volume.14 No. 11 p.1448 ~ p.1455
Caffeine Increases Sweating Sensitivity via Changes in Sudomotor Activity During Physical Loading
Kim Tae-Wook

Shin Young-Oh
Lee Jeong-Beom
Min Young-Ki
Yang Hun-Mo
Abstract
We assessed the effect of caffeine on sudomotor activity and sweating sensitivity during physical loading. Both physiological responses could occur due to energy expenditure. Subjects were 13 athletically trained males (22.1¡¾3.7 years old, 174.2¡¾5.4?cm tall, and weighing 70.9¡¾4.6?kg, with maximal oxygen consumption [VO2max] of 53.6¡¾4.4?mL/kg/minute). The study involved a within-subject, random, crossover design. Tests were performed following the ingestion of 3?mg/kg caffeine. The physical loading involved running for 30 minutes at 60% VO2max (24.0¡¾0.5¡ÆC, 40¡¾3.0% relative humidity). Tympanic temperature (TYMP) was significantly higher in the caffeine-consuming group (Caffe-I) at pre-exercise (40 minutes after caffeine intake and immediately before running) (P<.05). Mean body temperature (mTb) was significantly higher in the Caffe-I group at pre- and post-exercise (30 min after start of running) (P<.05). Onset time of localized sweating was significantly shorter in the Caffe-I group (P<.01), but localized sweat volume and active sweat gland output (per single gland) was significantly higher in the Caffe-I group (P<.001). Activated sweat gland density was significantly increased in the Caffe-I group on the abdomen and thigh (P<.01). In conclusion, caffeine ingestion caused not only increases in TYMP and mTb through thermogenesis, but also an increased sweating sensitivity via changes in sudomotor activity.
KEYWORD
acetylcholine, mean body temperature, sweat gland density, tympanic temperature
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